Drug Name: testosterone propionate
English name: Testosterone Propionate
Function of the role:
Role and testosterone, methyltestosterone same, but the duration of action than intramuscular lasting injections every 2 to 3 days once. Clinically applicable testis syndrome, cryptorchidism, male hypogonadism; gynecological diseases menorrhalgia, uterine fibroids; senile osteoporosis and aplastic anemia. By stimulating the kidneys secrete erythropoietin role or have a direct stimulating effect on the bone marrow. Primary testicular hypofunction androgen replacement therapy; genital dysplasia.
Large doses can cause virilization, edema, liver damage, jaundice, and dizziness. Allergic reactions should be discontinued. Liver and kidney dysfunction, prostate cancer patients and pregnant women hanged. If crystals have formed injection, can be heated dissolved injections. Delayed puberty and dwarfism; variety of chronic wasting disease.
Consumption usage:
Intramuscular: 1 is typically 25mg, 2 to 3 times a week. Androgen Deficiency: intramuscular injection of 10 ~ 50mg, 2 or 3 times a week. Menorrhagia or uterine fibroids: Each intramuscular injection 25 ~ 50mg, 2 times a week. Dysfunctional uterine bleeding, with progesterone use: Each intramuscular injection 25 ~ 50mg, every other day, a total of 3 to 4 times. Aplastic Anemia: intramuscular injection of 1 day or every other day 100mg, once every six months or more. Senile Osteoporosis: Every intramuscular 25mg, 2 to 3 times a week, once every three to six months.
Women with breast cancer and bone metastases in breast cancer: Each intramuscular injection 50 ~ 100mg, every other day, medication 2 to 3 months. Large doses can cause virilization, edema, liver damage, jaundice, and dizziness. Allergic reactions should be discontinued. Liver and kidney dysfunction, prostate cancer and pregnant women hanged. If crystals have formed injection, can be heated dissolved injections. Pregnant and lactating women, prostate cancer patients with disabling; medication should regularly check liver function, liver damage if you should reduce the dosage or disabled; prepubescent children should be applied in reduction, and every 6 months bone age measured 1 . Injection: Each 10mg (1ml), 25mg (1ml), 50mg (1ml).
Characterized as:
This product is the first in vivo into 5α dihydrotestosterone (5α-dihyrotesterone), later with cell receptors, into the nucleus, chromatin function, activation of RNA polymerase, promote protein synthesis and cell metabolism. In addition, testosterone propionate by erythropoietin stimulate red blood cell formation and differentiation. Although this product can be absorbed orally, but will quickly destroy the liver and failure, it is generally used intramuscular injection. After intramuscular injection of testosterone propionate, slow absorption, and its delay onset time 2-4 days. In the blood, 98% of testosterone and sex hormone binding globulin, only 2% of free form. Half-life of 10-20 minutes. Testosterone inactivated in the liver, metabolites androsterone and DHEA original bile alkyl ketones. 90% of them with glucuronic acid and sulfuric acid combined form from the urine. Approximately 6% of the product is non-binding form by the bile, which can still be a small part of resorption, formation of enterohepatic circulation.
Adverse reactions:
17-α alkyl substituted testosterone has some toxicity to the liver and can cause jaundice. Long been used in female patients may cause acne, hirsutism, deepening voice, changes in libido and other masculine performance. When they find liver dysfunction and female masculine performance, should be discontinued immediately. Large doses can cause virilization, edema, liver damage, jaundice, and dizziness.
Allergic reactions should be discontinued. Liver and kidney dysfunction, prostate cancer and pregnant women hanged. If crystals have formed injection, can be heated dissolved injections. Pregnant and lactating women, prostate cancer patients with disabling; medication should regularly check liver function, liver damage if you should reduce the dosage or disabled; prepubescent children should be applied in reduction, and every 6 months bone age measured 1 .
Drug use:
Promote the formation of the male sex organs, development, maturation, and unopposed estrogen, inhibiting the growth of endometrial and ovarian pituitary function. Promote protein synthesis and metabolism, excitement bone marrow function, stimulate blood cell formation. Clinically used for male hypogonadism, and cryptorchid testis syndrome symptoms; gynecological diseases, menorrhalgia, uterine fibroids, endometriosis, osteoporosis and pediatric aplastic anemia.
Usage and dosage: Each tablet 5mg, adult oral general day 2 times a day every 1-2 tablets or sublingual, 2 times a day every one. Male androgen deficiency: oral one day 6-20 tablets, maintenance dose one day 4-12 tablets. Menorrhagia or uterine fibroids: sublingual tablets every 1-2 2 times a day, and even served 3-6 months. Aplastic anemia in children: one day per kilogram of body weight 1-2mg, once or divided into 2 doses.
Side effects and precautions: Female long-term use in patients with more than 60 per month can cause acne, hirsutism, deepening voice, and changes in libido. Liver, kidney heart dysfunction with caution. Prostate cancer is disabled, pregnant women and lactating hanged.
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