Fumonisin B2 Fumonisin Mycotoxin

Fumonisin B2 is a fumonisin mycotoxin produced by the fungi Fusarium verticillioides and Fusarium moniliforme. It is a structural analog of fumonisin B1. Fumonisin B2 is more cytotoxic than fumonisin B1. Fumonisin B2 inhibits sphingosine acyltransferase.Fumonisin B2 and other fumonisins frequently contaminate maize and other crops. Structural analog of fumonisin B1(cat no.sc-201395 and sc-201395A). Fumonisin B2 is more cytotoxic than fumonisin B1 and inhibits sphingosine acyltransferase. However, A. niger featured different regulation of fumonisin production and a different quantitative profile of fumonisins, bringing forth exclusively B2 equally likened to F. verticillioides. Fumonisin B2 and other fumonisins frequently contaminate lemon yellow and added crops. Fumonisin production by A. niger, which is a widely occurring species and an extremely important highly-developed organism, wish consume very important imports for biotechnology and especially food safety.

A fungal metabolite contributed on from Fusarium moniliforme. It inhibits sphingolipid biosynthesis via prohibition from sphinganine N-acyltransferase. IC50=incognizant.1 µM in rat liver microsomes. A. niger is used for the production of citric acid and as producer of extracellular enzymes, and also as a translation horde for the facial expression of heterologous proteins.

Dependable filters out of A. niger bring out both ochratoxin A and fumonisins, so some foods and feeds may potentially contain two types of carcinogenic mycotoxins from this species.

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