Brevianamide A is metabolite of Penicillium viridicatum. One of the major secondary metabolites in Penicillium spores, they are responsible for inflammatory response in lung cells. Both were found to fluoresce under long-wave ultraviolet radiation.
Boost branches of knowledge demoed that a minor lowly metabolite, brevianamide B, has an epimeric center at the spiro-indoxyl quaternary centre on. Both were found to fluoresce under long-wave ultraviolet radiation. Furthermore, under irradaton, brevianamide A has equalled established to isomerize to brevianamide Bacilli. Furthermore, under irradaton, brevianamide A has been shown to isomerize to brevianamide B.
When Penicillium brevicompactum was adult betwixt layers of dialysis tissue layer during Czapek-Dox agar for 3 days, no deductive reasoning of mycophenolic battery-acid, brevianamide A, asperphenamate, or ergosterol fell out. Later removal of the upmost tissue layer layer, airy mycelium developed and all four metabolites weremaded. The bulk of the mycophenolicbattery-acidd that was formed was excreted into the medium, the majority from the brevianamide A and asperphenamate equalled found in the aerial hyphae, and ergosterol was base inwards both vegetational and aerial mycelia.
Brevianamides A and B are among at least four yellow metabolites that may be formed by isolates of P. viridicatum.
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