Thursday, July 4, 2013

About Testosterone Cypionate


Testosterone - Cypionate
(Testosterone cypionate)
Testosterone is a male hormone, so, then, man! In this configuration file, we will look at testosterone cypionate, and examine the advantages and disadvantages in order to improve its use in athletics and bodybuilding show.
Testosterone is many different physiological and psychological characteristics of men responsible. It promotes sex Drive, fat loss, helps achieve and maintain lean muscle mass, bone density and may even prevent heart disease. (1) All other steroid is actually changed testosterone molecule has been changed hormonal properties. This causes testosterone today, athletes employ all other steroids "Father." In fact, testosterone is anabolic / male ratio we use, this is a "perfect" 100 points, and in this respect our standards to measure all other steroids.

As I mentioned earlier, testosterone is a highly androgenic steroid, and it has an anabolic (muscle building) 100 level, making it a good drug to use if one in size and strength of the pursuit. If you do not have more size and strength of the pursuit, then why would you read it, right? Well, let's face reality, to see in the end is what makes testosterone a good mass builder. Firstly, testosterone can promote muscle (2) more muscle nitrogen nitrogen retention have more muscle protein stores. Testosterone can also increase the other anabolic hormone, IGF - 1 levels in muscle tissue (3). Testosterone also has the amazing ability to increase the satellite cells (4) activities. These cells to repair damaged muscles are very active role. Testosterone also androgen receptor, promotes muscle gain and fat loss, (5) also significantly increased the concentration of A ṛ cells repair and growth of muscle and muscle Airport Railway key. (4,6 iron-dependent mechanisms). Shape change induced by testosterone, can change the appearance and size of muscle fibers (7) number. Androgens such as testosterone can be protected from decomposition (muscle wasting your hard earned muscle) glucocorticoid hormones (8), thus inhibiting their actions. In addition, testosterone has been oxygenated blood through a better ability to increase red blood cell production (9), red blood cell count and a higher endurance can be improved. More RBCs can also improve from strenuous physical activity recovery. As you may have suspected, Testosterones' Anabolic / androgenic effects of dose dependent, the higher the dose the higher the muscle building effect (10).

Steroid.com members report heavy use strength gains, and testosterone (11). Testosterone neutrons by increasing muscle movement (4), to improve neuromuscular transmission (12) the number of muscle contraction. It also promotes glycogen synthesis (13) providing more endurance and strength training to improve fuel intense. Also note that the use of water from testosterone can cause muscle rebound when compressed in a weight reduction. Testosterone promote aggression and dominance behavior (14), which would explain the psychological advantage of athletes confidence they need to be heavy iron.
Testosterone is also good at promoting fat loss. There is an anti-estrogen effect it creates an ideal fat loss environment. Test combined with the collapse of fat causes fat cells AR and also prevents new fat formation. (15) Another test of the indirect loss of fat, the action affect its nutritional meal muscle and fat. Because the body is built on a faster speed on the foods you eat more muscle is the muscle tissue in the shuttle, away from fat.
Testosterone what not to do?
Side effects Testosterone Cypionate
Testosterone use also some unwelcome side effects are Steroid.com members should be aware of. Testosterone can be converted to the female hormone estrogen via aryl () by the aromatase enzyme. Excessive estrogen can cause some nasty side effects. Male breast tissue growth (breast), fat gain and reduced fat breakdown, libido, testicular atrophy and loss of water retention. Water can increase blood pressure weakening blood vessels over time. Use of a class of these drugs to block estrogen stops the conversion of testosterone to estrogen easily be called aromatase inhibitors side effects. In a cycle of testosterone can prevent testicular atrophy using human chorionic gonadotropin. Testosterone can also 5α-reductase enzyme. This operation is converted to testosterone, dihydrotestosterone (DHT), there are more parents in the form of the male hormone. One is of DHT on the hair loss cause users who suffer male pattern baldness of the scalp tissue with high affinity. May influence of DHT, and prostate, causing it to swell. This can cause swollen glands press on the bladder causing urinary problems. Drugs called 5alpha - reductase inhibitors can prevent not prevent testosterone anabolic affect these symptoms. (16) high doses of the test can also negatively affect cholesterol, reduced HDL (17), continue to ignore this may cause a number of serious health problems the road.
Testosterone levels decrease, because the level of the age of 50-60 years greatly (18) down. Low-level test induced muscle mass and strength, fat loss in income and libido (18) loss. It is a good idea to replace the external source of testosterone. Supplemented with sub-optimal levels may prevent or delay Alzheimer's disease and other cognitive diseases of the elderly testosterone, neuroprotection, regeneration of motor units, improve mood, memory, appetite, libido, increase bone mass and reduce the risk of heart attack and stroke (19) (20) (21) (22). This indicates that testing alternative significantly improve the quality of life, it may be a good choice for middle-aged men. Readers should note that the use of high doses of downside risks increase as a side effect. (23)
Testosterone cypionate is an injectable testosterone ester oils contain molecules attach to testosterone cypionate. Esters indicates that the test mode is released after it is injected into the body. This particular ester gives the testosterone an active life of 15-16 days, although blood levels of this drug fall sharply five days post-administration, testosterone levels are still above baseline after a week (24). Stable blood concentration can be achieved with weekly injections. Steriod.com members often twice-weekly drug administration or every 3-5 days. In an interesting side note, many users believe that the cytochrome P450 steroid test is more or less than the other popular injectable testosterone enanthate powerful. The fact is that they are almost identical in release mode, so almost no difference between the two. However, as early as the first underground steroid handbook printing, there are rumors that Arcuate has more than Enth more "kick."



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Tuesday, July 2, 2013

About 4-Hydroxy Testosterone Acetate



4-Hydroxy Testosterone Acetate

Chemical Name: 4-Androsten-4, 17β-ol-3-one Acetate

Molecular weight: 346.46

Properties: white crystalline powder

CAS: 305-84-0

Purity: ≥ 99%

Usage: it has antioxidant activity, is a accustomed anti-oxidants. For beef
aggressive to oxidation, to advance the body's PH balance, extend corpuscle life



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Sunday, June 30, 2013

About Testosterone Propionate




Drug Name: testosterone propionate
English name: Testosterone Propionate

Function of the role:

Role and testosterone, methyltestosterone same, but the duration of action than intramuscular lasting injections every 2 to 3 days once. Clinically applicable testis syndrome, cryptorchidism, male hypogonadism; gynecological diseases menorrhalgia, uterine fibroids; senile osteoporosis and aplastic anemia. By stimulating the kidneys secrete erythropoietin role or have a direct stimulating effect on the bone marrow. Primary testicular hypofunction androgen replacement therapy; genital dysplasia.
Large doses can cause virilization, edema, liver damage, jaundice, and dizziness. Allergic reactions should be discontinued. Liver and kidney dysfunction, prostate cancer patients and pregnant women hanged. If crystals have formed injection, can be heated dissolved injections. Delayed puberty and dwarfism; variety of chronic wasting disease.

Consumption usage:

Intramuscular: 1 is typically 25mg, 2 to 3 times a week. Androgen Deficiency: intramuscular injection of 10 ~ 50mg, 2 or 3 times a week. Menorrhagia or uterine fibroids: Each intramuscular injection 25 ~ 50mg, 2 times a week. Dysfunctional uterine bleeding, with progesterone use: Each intramuscular injection 25 ~ 50mg, every other day, a total of 3 to 4 times. Aplastic Anemia: intramuscular injection of 1 day or every other day 100mg, once every six months or more. Senile Osteoporosis: Every intramuscular 25mg, 2 to 3 times a week, once every three to six months.
Women with breast cancer and bone metastases in breast cancer: Each intramuscular injection 50 ~ 100mg, every other day, medication 2 to 3 months. Large doses can cause virilization, edema, liver damage, jaundice, and dizziness. Allergic reactions should be discontinued. Liver and kidney dysfunction, prostate cancer and pregnant women hanged. If crystals have formed injection, can be heated dissolved injections. Pregnant and lactating women, prostate cancer patients with disabling; medication should regularly check liver function, liver damage if you should reduce the dosage or disabled; prepubescent children should be applied in reduction, and every 6 months bone age measured 1 . Injection: Each 10mg (1ml), 25mg (1ml), 50mg (1ml).

Characterized as:

This product is the first in vivo into 5α dihydrotestosterone (5α-dihyrotesterone), later with cell receptors, into the nucleus, chromatin function, activation of RNA polymerase, promote protein synthesis and cell metabolism. In addition, testosterone propionate by erythropoietin stimulate red blood cell formation and differentiation. Although this product can be absorbed orally, but will quickly destroy the liver and failure, it is generally used intramuscular injection. After intramuscular injection of testosterone propionate, slow absorption, and its delay onset time 2-4 days. In the blood, 98% of testosterone and sex hormone binding globulin, only 2% of free form. Half-life of 10-20 minutes. Testosterone inactivated in the liver, metabolites androsterone and DHEA original bile alkyl ketones. 90% of them with glucuronic acid and sulfuric acid combined form from the urine. Approximately 6% of the product is non-binding form by the bile, which can still be a small part of resorption, formation of enterohepatic circulation.

Adverse reactions:

17-α alkyl substituted testosterone has some toxicity to the liver and can cause jaundice. Long been used in female patients may cause acne, hirsutism, deepening voice, changes in libido and other masculine performance. When they find liver dysfunction and female masculine performance, should be discontinued immediately. Large doses can cause virilization, edema, liver damage, jaundice, and dizziness.
Allergic reactions should be discontinued. Liver and kidney dysfunction, prostate cancer and pregnant women hanged. If crystals have formed injection, can be heated dissolved injections. Pregnant and lactating women, prostate cancer patients with disabling; medication should regularly check liver function, liver damage if you should reduce the dosage or disabled; prepubescent children should be applied in reduction, and every 6 months bone age measured 1 .

Drug use:

Promote the formation of the male sex organs, development, maturation, and unopposed estrogen, inhibiting the growth of endometrial and ovarian pituitary function. Promote protein synthesis and metabolism, excitement bone marrow function, stimulate blood cell formation. Clinically used for male hypogonadism, and cryptorchid testis syndrome symptoms; gynecological diseases, menorrhalgia, uterine fibroids, endometriosis, osteoporosis and pediatric aplastic anemia.
Usage and dosage: Each tablet 5mg, adult oral general day 2 times a day every 1-2 tablets or sublingual, 2 times a day every one. Male androgen deficiency: oral one day 6-20 tablets, maintenance dose one day 4-12 tablets. Menorrhagia or uterine fibroids: sublingual tablets every 1-2 2 times a day, and even served 3-6 months. Aplastic anemia in children: one day per kilogram of body weight 1-2mg, once or divided into 2 doses.
Side effects and precautions: Female long-term use in patients with more than 60 per month can cause acne, hirsutism, deepening voice, and changes in libido. Liver, kidney heart dysfunction with caution. Prostate cancer is disabled, pregnant women and lactating hanged.


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Friday, June 28, 2013

About Clostebol acetate




Name:Clostebol Acetate

CAS:855-19-6

MF: C21H29ClO3

MW: 364.91

purity:98% 4-Chlorotestosterone acetate

Appearance:withe apparent powder

Clostebol Acetate is constructed androgen and accept a accessible gray assimilation effection,but anemic in androphay effection,4-Chlorotestosterone acetate can advance synthetizing the portein ,improve appetite,improve energy.so Clostebol Acetate is mainly acclimated in malnutrition

product details:

product name:Clostebol Acetate CAS:855-19-6 purity:98% 4-Chlorotestosterone acetate Appearance:withe apparent crumb Clostebol Acetate is constructed androgen and accept a accessible gray assimilation effection,but anemic in androphay effection,4-Chlorotestosterone acetate can advance synthetizing the portein ,improve appetite,improve energy.so Clostebol Acetate is mainly acclimated in malnutrition I am a god supplier,wish you can email me and let me acquaint my business for you ,I thik you will be annoyed Supply list: Testosterone Base Methyltestosterone Testosterone Propionate Testosterone decanoate Testosterone Undecanoat Testosterone Cypionatee Testosterone isocaproate Testosterone Enanthate Testosterone Phenylpropionate Sustanon250 powder(mixed testosterone) Clostebol Acetate Testosterone Acetate Mesterolone Boldelone Boldenone undecylenate Boldelone Acetate ester Nandrolone Phenylpropionate Nandrolone Decanoate Drostanolone Enanthate Drostanolone propionate(Masteron) Oxandrolone(anavar) Oxymetholone(Anadrol) Metandienone(Dianabol) Stanozolol(winstrol) Trenbolone Enanthate Trenbolone Acetate Methenolone Enanthate Methenolone Acetate Chlordehydromethyltestosterone(Turinabol) Dutasteride Finasteride Tamoxifen Citrate(Nolvadex) Raloxifene Clomifene citrate(cClomiphene) letrozole Vardenafil Sildenafil Tadalafil Exemestane( Aromasin)

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Wednesday, June 26, 2013

What is Nandrolone Phenypropionate?



Nandrolone Phenypropionate 17b-hydroxyestr-4-en-3-one 17-(3-phenylpropionate) Basic advice Product Name: 17b-hydroxyestr-4-en-3-one 17-(3-phenylpropionate) Synonyms: NANDROLONE PHENPROPIONATE;NANDROLONE PHENYLPROPIONATE;NANDROLONI PHENYLPROPIONAS;17-(1-oxo-3-phenylpropoxy)estr-4-en-3-one;17-beta-hydroxyestr-4-en-3-one hydrocinnamate;17-beta-hydroxy-estr-4-en-3-onhydrocinnamate;17-beta-hydroxy-estr-4-ene-3-on3-phenylpropionate;17-beta-Hydroxy-estra-4-en-3-one, 17-phenylpropionate CAS: 62-90-8 heatherwang520(at)gmail(dot)com MF: C27H34O3 MW: 406.56 EINECS: 200-551-9 Product Categories: Steroids;Intermediates & Fine Chemicals;Pharmaceuticals;Steroid and Hormone Mol File: 62-90-8.mol 17b-hydroxyestr-4-en-3-one 17-(3-phenylpropionate) Chemical Properties mp 85-87 centigrade accumulator temp. Controlled Substance, -20 centigrade Freezer CAS DataBase Reference 62-90-8(CAS DataBase Reference) NIST Chemistry Reference 4-Androstene-17-beta-ol-3-one, 19-nor-delta-, phenylpropionate(62-90-8) Delivery and shipping: 1. Minimum Order: 10g 2. Packaging: Pack in artificial bag, again in a antithesis bag 3. Payment: Western Union, Money gram 4. Shipping: EMS, DHL, FedEx, UPS or TNT 5. Delivery Time: Around 7days afterwards transaction 6. Appearance: White or Similar apparent crumb 7. Storage: Accumulate abroad from blaze and calefaction source; hermetically deposit; accumulate in shady, air-conditioned and dry condition; assure adjoin the tide. 8. Sizes: 50g, 100g, 500g, 1kg antithesis bag or Customized 9. Application: Pharmaceutical and biochemical analysis Reference price: USD 1150/kg Please forward me email if you are absorbed in our articles or accept any questions.My email abode is above.

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Sunday, June 23, 2013

What is 17a-Methyl-1-Testosterone?



17a-Methyl-1-Testosterone
Chinese Name: A testosterone
Chinese Synonyms: methyl-17Β-hydroxy - androst-4 - en - 3 - one; 17 - methyltestosterone; methyl testosterone / methyl-17Β-hydroxy - androst-4 - en - 3 - one; 17 - Α-methyl testosterone; dimethyl testosterone; 17a-methyl-17b-hydroxy-androst-4 - en - 3 - one; methyltestosterone; methyltestosterone
Product Name: 17a-Methyl-1-Testosterone
English Synonyms: METANDREN; MESTERONE; METHYLTESTOSTERONE; 4-ANDROSTEN-17ALPHA-METHYL-17BETA-OL-3-ONE; 17ALPHA-METHYLTESTOSTERONE; 17ALPHA-METHYL-4-ANDROSTEN-17BETA-OL-3-ONE; 17-METHYLTESTOSTERONE; 17BETA -HYDROXY-17ALPHA-METHYL-4-ANDROSTEN-3-ONE
CAS Number: 58-18-4
MF: C20H30O2
Molecular Weight: 302.45
EINECS Number: 200-366-3
Related Categories: Hormone; biochemical reagents; biochemicals; carbonyl compounds; Steroids; API's; Intermediates & Fine Chemicals; Pharmaceuticals; Steroid and Hormone
Mol File: 58-18-4.mol



Methyltestosterone nature
Mp 162-168 ° C (lit.)
Specific rotation 79 º (c = 1, alcohol)
Flash Point 5 ° C
Storage conditions 2-8 ° C
Solubility in H2O: ≤ 0.5 mg / mL
form solid (photosensitive)
color white
Merck 13,6148
CAS DataBase 58-18-4 (CAS DataBase Reference)
NIST Chemistry 17 (Alpha)-methyl-delta4-androsten-17-(beta)-ol-3-one (58-18-4)
EPA Substance Androst-4-en-3-one, 17-hydroxy-17-methyl-, (17.beta.) - (58-18-4)


A testosterone Usage And Synthesis
Chemical Properties white crystalline powder, odorless, tasteless, hygroscopic, deterioration of light. Mp161-166 ℃; Specific rotation [α] 25D 69 ° - 75 ° (dioxane); ethanol solution at 240nm wavelength of maximum absorption. Chlorine and soluble in dioxane, was dissolved in ethanol (1:5), acetone (1:10), methanol, slightly soluble acetate, insoluble in water, vegetable oil.
Uses biochemical studies, the male hormone drugs.
Use androgen medicines for testosterone hormone deficiency replacement therapy can also be used functional uterine bleeding, aplastic anemia and other diseases treatment.
Megestrol acetate double production methods pregnenolone oxime by hydroxylamine, POCl3 Beckmann rearrangement, acetic acid hydrolysis of dehydroepiandrosterone androsterone, the latter with methyl magnesium iodide Grignard reaction, and then oxidized aluminum isopropoxide obtained.
CAS: 58-18-4
MF: C20H30O2
Molecular Weight: 302.45
Melting point: 162-168 ℃
Chinese Name: A methyl testosterone hormone testosterone methyltestosterone methyltestosterone
Product Name :17-Methyltestosterone
Nature Description: white crystalline powder, melting point 162-168 ℃, specific rotation 79 º (C = 1, ALCOHOL)
Uses: androgen medicines for testosterone hormone deficiency replacement therapy can also be used functional uterine bleeding, aplastic anemia.

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Promote the formation of the male sex organs, development, maturation, and unopposed estrogen, inhibiting the growth of endometrial and ovarian pituitary function. Promote protein synthesis and metabolism, excitement bone marrow function, stimulate blood cell formation. Clinically used for male hypogonadism, and cryptorchid testis syndrome symptoms; gynecological diseases, menorrhalgia, uterine fibroids, endometriosis, osteoporosis and pediatric aplastic anemia.


From:Hormones Chemicals

Sunday, June 16, 2013

Phosphorylase kinase gamma PHKG1 Monoclonal Antibody 2G6 features

Phosphorylase kinase gamma PHKG1 Monoclonal Antibody 2G6 is a chic of protein phosphorylation catalyzed acknowledgment of the enzyme. It can adenosine triphosphate (ATP) on the γ-phosphate transferred to the protein molecules of the amino acerbic residues. In a lot of cases, this occurs in the phosphorylation of proteins on serine residues. 50 years appeared appellation refers to protein kinase catalytic casein, phosvitin or added protein phosphorylation of the enzyme. In the 1970s a dozen beastly tissues and organs aswell begin a actual important chic of protein kinase - circadian adenosine monophosphate (cAMP) protein kinase, after in the insects and E. coli accept been reported. Protein kinase in beef broadcast throughout the nucleus, mitochondria, microsomes and cytosol. Generally disconnected into three categories. ① protein kinase substrate specificity: If phosphorylase kinase, pyruvate dehydrogenase kinase. ② circadian nucleotide abased protein kinase: If circadian adenosine monophosphate (cAMP) protein kinase, circadian guanosine monophosphate (cGMP) protein kinases. ③ added protein kinases: eg histone kinase. cAMP to actuate protein kinase activated and non-organisms present in two forms, their accommodation controlled by a array of hormone regulation. cAMP protein kinase is composed of 4 subunits - two cAMP bounden with the authoritative subunit (R) and two non-activated phosphate groups able of catalyzing the alteration of the catalytic subunit (C). If the absorption of intracellular cAMP cAMP kinase break into subunits and two adjustable bifold catalytic subunit activation. The donor protein kinase activator of ATP and calcium (Ca2) in the attendance of low action can phosphorylation of phosphorylase kinase, it becomes top phosphorylase kinase activity, which in about-face can lower the action of acerbic b The change in agitator phosphorylation action of phosphorylase a top a, so that the abasement of glycogen smoothly.

Phosphorylase kinase gamma PHKG1 Monoclonal Antibody 2G6 ATP and the donor activator calcium (defendant) in the attendance of low action can phosphorylation of phosphorylase kinase, it becomes top phosphorylase kinase activity, the closing can the low action by phosphorylation of phosphorylase b adapted into a awful alive phosphorylase a, so that the abasement of glycogen smoothly. At the aforementioned time, and accomplish the top protein kinase action of a phosphorylation of glycogen synthase a low action of glycogen synthase b, to apathetic down the glycogen synthesis. So that beneath the adjustment of cAMP absorption in the accumulation and abasement of glycogen metabolism in balance. 1980s begin a tyrosine protein kinase, which catalyzes autophosphorylation can be phosphorylated added proteins. Phosphorylation acknowledgment which occurs in assertive specific hydroxyl accumulation of tyrosine. The alteration of assertive bump virus proteins and some advance agency receptor protein tyrosine kinase activity. Before the analysis of plant-based protein kinase antecedent three categories. The Stone and Walker (1995) based on the amino acerbic arrangement of protein kinase catalytic arena similarity, the plants were disconnected into 5 groups of protein kinase. This 5 histone kinase were ① AGC group: cAMP (cyclic adenosine monophosphate)-dependent protein kinase PKA, cGMP (cyclic guanosine monophosphate)-dependent protease PKG and calcium-dependent protein kinase PKC lipid represented to be additional messengers (such as cAMP, cGMP, DAG (diacylglycerol) and Ca2) is characterized by activation. ② CaMK Group: including Ca2 / CaM-dependent protein kinase CaMK, Ca abased and CaM-dependent protein kinase CDPK not so abased on the additional agent protein kinase is the absoluteness of the group. ③ CMGC Group: including MAPK (mitogen-activated protein kinase), CDK (cyclin-dependent protein kinase), etc., about to the antecedent two histone kinase abased on the additional messenger, the accumulation acts on the after kinase phosphorylation avalanche arrangement .

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