17a-Methyl-1-Testosterone
Chinese Name: A testosterone
Chinese Synonyms: methyl-17Β-hydroxy - androst-4 - en - 3 - one; 17 - methyltestosterone; methyl testosterone / methyl-17Β-hydroxy - androst-4 - en - 3 - one; 17 - Α-methyl testosterone; dimethyl testosterone; 17a-methyl-17b-hydroxy-androst-4 - en - 3 - one; methyltestosterone; methyltestosterone
Product Name: 17a-Methyl-1-Testosterone
English Synonyms: METANDREN; MESTERONE; METHYLTESTOSTERONE; 4-ANDROSTEN-17ALPHA-METHYL-17BETA-OL-3-ONE; 17ALPHA-METHYLTESTOSTERONE; 17ALPHA-METHYL-4-ANDROSTEN-17BETA-OL-3-ONE; 17-METHYLTESTOSTERONE; 17BETA -HYDROXY-17ALPHA-METHYL-4-ANDROSTEN-3-ONE
CAS Number: 58-18-4
MF: C20H30O2
Molecular Weight: 302.45
EINECS Number: 200-366-3
Related Categories: Hormone; biochemical reagents; biochemicals; carbonyl compounds; Steroids; API's; Intermediates & Fine Chemicals; Pharmaceuticals; Steroid and Hormone
Mol File: 58-18-4.mol
Methyltestosterone nature
Mp 162-168 ° C (lit.)
Specific rotation 79 º (c = 1, alcohol)
Flash Point 5 ° C
Storage conditions 2-8 ° C
Solubility in H2O: ≤ 0.5 mg / mL
form solid (photosensitive)
color white
Merck 13,6148
CAS DataBase 58-18-4 (CAS DataBase Reference)
NIST Chemistry 17 (Alpha)-methyl-delta4-androsten-17-(beta)-ol-3-one (58-18-4)
EPA Substance Androst-4-en-3-one, 17-hydroxy-17-methyl-, (17.beta.) - (58-18-4)
A testosterone Usage And Synthesis
Chemical Properties white crystalline powder, odorless, tasteless, hygroscopic, deterioration of light. Mp161-166 ℃; Specific rotation [α] 25D 69 ° - 75 ° (dioxane); ethanol solution at 240nm wavelength of maximum absorption. Chlorine and soluble in dioxane, was dissolved in ethanol (1:5), acetone (1:10), methanol, slightly soluble acetate, insoluble in water, vegetable oil.
Uses biochemical studies, the male hormone drugs.
Use androgen medicines for testosterone hormone deficiency replacement therapy can also be used functional uterine bleeding, aplastic anemia and other diseases treatment.
Megestrol acetate double production methods pregnenolone oxime by hydroxylamine, POCl3 Beckmann rearrangement, acetic acid hydrolysis of dehydroepiandrosterone androsterone, the latter with methyl magnesium iodide Grignard reaction, and then oxidized aluminum isopropoxide obtained.
CAS: 58-18-4
MF: C20H30O2
Molecular Weight: 302.45
Melting point: 162-168 ℃
Chinese Name: A methyl testosterone hormone testosterone methyltestosterone methyltestosterone
Product Name :17-Methyltestosterone
Nature Description: white crystalline powder, melting point 162-168 ℃, specific rotation 79 º (C = 1, ALCOHOL)
Uses: androgen medicines for testosterone hormone deficiency replacement therapy can also be used functional uterine bleeding, aplastic anemia.
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Promote the formation of the male sex organs, development, maturation, and unopposed estrogen, inhibiting the growth of endometrial and ovarian pituitary function. Promote protein synthesis and metabolism, excitement bone marrow function, stimulate blood cell formation. Clinically used for male hypogonadism, and cryptorchid testis syndrome symptoms; gynecological diseases, menorrhalgia, uterine fibroids, endometriosis, osteoporosis and pediatric aplastic anemia.
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From:Hormones Chemicals
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